Objective To study the static inhalation toxicity of plastic racetrack surface materials in rats. Methods SD rats that passed quarantine inspection were randomly divided into four groups, namely 30 day normal control, 30 day exposure group, 90 day normal control, and 90 day exposure groups with 16 males and females in each group. Rats were exposed to gases by inhalation for 30 or 90 days. At the end of inhalation exposure, blood coagulation, blood routine test, blood biochemistry, organ coefficient, and organ pathology were assessed. Results Compared with normal control group of the same sex, thrombin time of male rats was shortened in the 30 day exposure group (P<0.05) and activated partial thrombin time of female rats was prolonged in the 90 day exposure group (P<0.01). Serum Ca and P were decreased in female rats (P<0.05, P<0.01), and serum creatinine and urea nitrogen (BUN) in rats were increased in the 30 day exposure group. In the 90 day exposure group, serum BUN and P were increased (P<0.05, P<0.01), Na and Cl were decreased of female rats (P<0.01), whereas serum BUN and total protein were increased in male rats (P< 0.05). The adrenal coefficient of male rats was increased in 30 and 90 day exposure groups (P<0.01). In the 30 day exposure group, there were three cases of mild steatosis of hepatocytes in the hepatic portal area, three cases of exfoliation of the bronchoalveolar epithelium, one case of renal cyst, and one case of individual convoluted tubule atrophy of testis. In the 90 day exposure group, there were six cases of mild steatosis of hepatocytes in the hepatic portal area, two cases of exfoliation of the bronchoalveolar epithelium, one case of cellular focal hypertrophy of adrenal zona fasciculata, two cases of individual convoluted tubule atrophy of the testis, two cases of individual glomerular telangiectasia of the kidney, one case of renal cyst, four cases of hyaline cast of the kidney, one case of mineralization, and one case of hydronephrosis. Conclusions The effects on the liver, lung, testis, and kidney of SD rats were slight after 30 days of inhalation exposure, while kidney damage was aggravated after 90 days of inhalation exposure.