Research progress of competing endogenous RNA in bronchial asthma
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Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Jiangsu University, Zhenjiang 212000, China

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R-33

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    Abstract:

    Bronchial asthma is a chronic inflammatory disease characterized by airway inflammation, hyper- responsiveness, and remodeling, which are manifested as recurrent wheezing or coughing and chest distress. Recent studies indicate that lncRNAs and circRNAs competitively sponge miRNAs via microRNA response elements, form a competing endogenous RNA regulatory network, and therefore regulate post-transcriptional gene expression and play a major regulating role in the development and progression of asthma. This article reviews the mechanisms of ceRNA and its effects on asthma.

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History
  • Received:May 11,2020
  • Revised:
  • Adopted:
  • Online: March 02,2021
  • Published: