The concept of "experimental animals" has been raised up, while we still need relevant laws and regulations on experimental animals. Accordingly, a potential safety hazard may occur when using these animals. Here we compare the content of the "Animal Epidemic Prevention Law of the People's Republic of China" and "Regulations for Experimental Animal Management", with the "Terrestrial Animal Health Code" issued by International Organisation for Animal Health (Office International des Epizooties,OIE), in order to provide some advice to completing the relevant laws in China.