Research progress of mouse models of focal cerebral stroke
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    Abstract:

    Stroke is a class of neurological disorders including cerebral ischemic stroke, cerebral hemorrhagic stroke (ICH) and subarachnoid hemorrhagic stroke (SAH), which has a high incidence of morbidity and mortality. Simple and reproducible animal model is indispensable for the study of pathogenesis and treatment after stroke insult. Location and size of injury, neurological deficits and cerebral blood flow changes can be used to assess the availability of the model for various treatment methods. Construction methods, designing experience as well as the methods of model assessment were summarized in this article.

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History
  • Received:
  • Revised:October 27,2014
  • Adopted:
  • Online: March 04,2015
  • Published: