Objective To measure the major organ weights and body weight in Juema minipigs, calculate the organ coefficient, and analyze the correlation between body weight and major organ weights. Methods The body weight and weight of 8 organs in 21 common 7-15-month old Juema minipigs (12 females and 9 males) were measured. The organ coefficients were calculated, and sex difference was analyzed by Student's t test. Linear regression, multivariable linear regression and multiple regression analysis were carried out to analyze the correlation between body weight and major organ weights using SAS software. Results There were no significant differences between males and females in body weight, organ weights and organ coefficients. Major organ weights were positively correlated to body weight determined by correlation analysis, and the weights of heart, liver, spleen, and kidney had significant positive correlation to body weight (P<0.05), and significant linear equations were established by linear regression analysis. The weights of heart and stomach showed significant direct correlation to body weight according to the multivariable linear regression analysis, and the most close correlation was found between the heart weight and body weight. Moreover, multiple regression analysis showed that the liver, lung, kidney and bladder had significant positive correlation with heart and stomach, and spleen had significant positive correlation with liver. Conclusion There are no significant differences between major organ coefficients in male and female Juema minipigs. There exists some linear relationship between main organ weights and body weight.