ObjectiveTo compare the difference between the electroretinogram (ERG) normal rhesus monkeys and humans, and provide a base for further study on the application of rhesus monkey retinal disease as an experiment mode1. Methods The electroretnogram (ERG) was recorded in 7 normal rhesus monkey (14 eyes) and 8 human (16 eyes). The recording items of ERG included rod response b wave, cone response, max response a and b waves, oscillatory potential O2,0Hz flicker ERG ΣP. The results were statistically tested. ResultsThe ERG waveform results in rhesus monkey are similar to those in humans, but the amplitudes were decreased and the implicit times were prolonged compared with the humans, and the differences in the amplitude of the Cone ERG and the flicker ERG were not statistically significant. ConclusionsThe retinal function in rhesus monkey is quite similar to those in humans in the ERG recording. Rhesus monkey is a good animal model for the study on human retinal disease especially the macular.