Objective To study the antihypertensive effects of s corn protein and its hydrolysates on spontaneously hypertensive rats (SHR)．MethodsSixty 6~8 week-old male SHR were randomly divided into 5 groups:group A (corn protein), group B (corn protein''s hydrolysate prepared with pepsin), group C(corn protein''s hydrolysate prepared with trypsin), group D (corn protein''s hydrolysate prepared with complex enzyme) and group E(saline). Each group were orally adiministered at dose of 1g/kg body weight. Subsequently, systolic blood pressure of SHR was measured at a fixed time interval (0,1, 2,4, 6 and 8 h) post-adiministration. ResultsResults showed that all hydrolysates had significant inhibition on blood pressure of SHR and compound enzyme hydrolysate had the strongest effect on antihypertension during 0~6 h, with SBP decreased significantly which compared with group A, B, C and E (P<0.01). ConclusionA significant decrease in systolic blood pressure of SHR was observed in group, B, C and D.