Abstract:Many identified functional genes in mammals are derived from mouse.There are about 140 mutations identified,since phenotype of cataract can be easily screened out.Spontaneous mutations are usually originated from large-scale animal breeding,and induced mutations are often obtained by radiation or ENU treatment.Sometimes,cataract can be found in knockout or transgenic mice.Known cataract genes,which are expressed in embryonic period,are known to be distributed on twenty chromosomes,and chromosome 1 harbors t...