Objective To study effect of high fat diet on serum chemistry and homogenized tissue chemistry on mice,and to construct the animal model for human coronary artery disease or other metabolism syndrome.Methods\ Total 63 C57BL/6j mice were randomly divided to 2 groups,feed high fat diet and standard chow diet for 67 days respectively,the body weight,food intake,serum and homogenized tissue chemistry,morphological characteristic was studied.Results(Mice feeding) high diet showed improved total cholesterol and l...