Abstract:Objective To investigate the effect of Morroniside which was isolated from Cornus of ficinalis on recovery of neurological function after focal cerebral ischemia reperfusion in rats.Methods Wistar male rats were randomly divided into sham operated group,model group and Morroniside-low(30 mg/kg),Morroniside-middle(90 mg/kg),Morroniside-high(270 mg/kg),vitamin E(35 mg/kg).Focal stroke was induced in adult rats by 30 minutes right middle cerebral artery occlusion reperfusion injury(tMCAO/R).To examine the reco...