Abstract:Objective To investigate the effect of Cortex Eucommiae on the fractures healing process. Methods Tibia fracture models were created in 45 rabbits. The animals were divided into experiment (n=23) and control groups (n=22). The experimental rabbits were intragastrically administered with Cortex Eucommiae and the control animals received the same amount of physiological saline. The fracture ends were taken for light microscopic examination on days 7, 17, 27, 37 and 47 of the experiment and the histopathological data were semi quantitatively analyzed. Results The light microscopic observation demonstrated that the repairing responses occurred earlier in the experimental group than that in control group. Conclusion The concentrated extracts of Cortex Eucommiae taken orally accelerates the healing process of fracture in rabbits.