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Research Progress on the Role of Microglia Efferocytosis in Alzheimer's Disease
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1.Department of Brain Disease, The First Affiliated Hospital of Henan University of Chinese Medicine;2.Department of Brain Disease Center, The First Clinical Medical College of Henan University of Traditional Chinese Medicine;3.Zhengzhou Jinshui District General Hospital;4.Zhengzhou Weilai Road Street Elder Care Center;5.Henan University of Chinese Medicine

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    Abstract:

    Microglia efferocytosis is the process by which microglia phagocytose damaged and dead cells, with anti-inflammatory and pro-damage repair effects. Recent studies have shown that microglia efferocytosis plays a crucial role in the pathogenesis of Alzheimer"s disease (AD) and may be a novel therapeutic target for AD. This paper reviews the relationship between microglia efferocytosis and AD pathogenesis and the potential of efferocytosis-related molecules as therapeutic targets for AD. The aim is to provide new ideas and approaches for the treatment of AD.

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History
  • Received:May 06,2024
  • Revised:May 21,2024
  • Adopted:August 02,2024
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