Objective : By comparing two different methods of establishing rat models of pressure uler, to explore a more suitable method for preparing animal models of pressure uler. Methods : 18 male SD rats were randomly divided into control group ( n = 6 ), model group A ( n = 6 ) and model group B ( n = 6 ). Control group : iodophor treatment was performed after hair removal at the simulated modeling site. Model A group : longitudinal compression was performed by simple deep tissue foreign body implantation ; model group B : transverse compression was performed by magnet compression method. The whole process time and each stage time of pressure uler model in each group were recorded. The general condition of rats was observed, and the molding rate, mortality rate and infection rate were compared. Results : The naked eye observed that the model A group and the model B group gradually appeared redness and swelling, ulceration, bleeding, exudation and necrosis. Comparison of the whole time of pressure uler in model group A and model group B : the difference between the two groups was statistically significant ( P0.05 ) ; the difference between the two groups was statistically significant ( P < 0.05 ). The difference between the two groups was statistically significant ( P < 0.05 ). There was significant difference between the two groups in stage IV ( P < 0.05 ). The mental and motor scores of the rats in the control group were significantly different from those in the model group A and the model group B ( P < 0.05 ). The general state of rats in model group A and model group B was significantly different, and the coat color was dim and the activity decreased. The model rate of rats in model A and model B was 100 %. The mortality and infection rate of model A group were higher than those of model B group, which were 33.34 % and 16.70 % respectively. Conclusion : Both methods can successfully prepare a four-stage model of pressure uler. The two methods have both commonalities and their own characteristics. The magnet compression method takes a short time, the rats are generally in good condition, and the mortality and infection rate are low. It is suitable for short-term intervention research ; the simple deep tissue foreign body implantation method takes a long time, requires rats to have a certain tolerance, has a high infection rate and a high mortality rate, and can be used in long-term observation of pressure uler rats.