Application and challenges for NHP laboratory animals in neuroscience
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1.institute of Medical Biology,Chinese Academy of Medical Science &2.amp;3.Peking Union Medical College

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the CAMS Innovation Fund for Medical Sciences (CIFMS, 2021-I2M-1-024). the Major Science and Technology Special Projects of Yunnan Province (202002AA100009) .Yunnan Province Technology Innovation Talent Training Object Project (202005AD160006). the Yunnan Fundamental Research Projects (grant No. 202001AS070047 and 2019FB101)

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    Abstract:

    【Abstract】: Currently, non-human primates (NHPs) are becoming increasingly important in laboratory animals, especially in the field of neuroscience, where many significant breakthroughs have been made, including research on brain development, neurodegenerative diseases and psychiatric disorders, but as their breeding and use grows, biosafety and animal ethics issues should be taken into account. This review summarizes the application and challenges of NHP laboratory animal in the neuroscience field from the aspects of NHP overview, feeding and operation, biosafety, and animal ethics.

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History
  • Received:April 19,2023
  • Revised:May 29,2023
  • Adopted:January 05,2024
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