Research progress on evaluation of type 2 diabetic peripheral neuropathy animal model
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Chengdu University of TCM

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    Abstract:

    Diabetic peripheral neuropathy is a common diabetic complication. At the moment, our understanding of its pathogenesis is incomplete, and there are no effective treatment options. In-depth research requires the use of animal experiments. The criteria for modeling success and the evaluation method for peripheral nerve function recovery are critical for carrying out animal experiments on type 2 diabetic peripheral neuropathy, but there is a lack of sorting out and analyzing the evaluation methods for type 2 diabetic peripheral neuropathy models. As a result, the author reviewed recent data, summarized and analyzed the evaluation methods of animal models of type 2 diabetic peripheral neuropathy from small and large nerve fibers, and proposed future development directions in order to provide a reference for related research.

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History
  • Received:April 18,2023
  • Revised:July 02,2023
  • Adopted:January 05,2024
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