Behavioral assessment in the parkinson’s model of nonhuman primates
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1.KUST;2.Institute of Primate Translational Medicine,Kunming University of Science and Technology

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    Abstract:

    Parkinson's disease is a neurodegenerative disease, can cause a series of patients with symptoms of movement and the movement, behind the pathogenesis is unclear, to explore the mechanism behind these phenotypic requires an appropriate animal model of rodents in the movement and the movement is very difficult to accurately simulate the patient symptoms, causes related to preclinical studies have limitations, in translational medicine. Non-human primate animal models can make up the gap between rodents and humans, thus the non-human primate PD model of movement and the movement symptoms, is very important to research on mechanism and therapy, this review summarizes the different behavior in quantitative way, and compared the advantages and disadvantages between different methods, for studying the PD monkey model provides a behavioral testing for help.

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History
  • Received:December 21,2022
  • Revised:June 25,2023
  • Adopted:September 05,2023
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