+Advanced Search
Home > Archive>Volume 34, Issue 10, 2024 >104-110,117. DOI:10.3969/j.issn.1671-7856.2024.10.013
PDF HTML XML Export Cite reminder
Research progress on the mechanism of D-galactose-induced brain aging model
Author:
Affiliation:

1. College of Basical Medical Science, Heilongjiang University of Chinese Medicine, Harbin 150040, China.2. Wuxi Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Wuxi 214071. 3. Heilongjiang University of Chinese Medicine, Harbin 150040

Clc Number:

R-33

  • Article
    • | |
  • Metrics
    • |
  • Reference
    • |
  • Related
    • |
  • Cited by
    • | |
  • Comments
    Abstract:

    As a normal physiological substance, D-galactose can induce a process similar to natural brain aging in vivo and in vitro when administered excessively, and thus it is widely used to induce brain aging models in China and abroad. The model of brain failure induced by D-galactose has the advantages of a short modeling time, low cost, and significant effect. However, the induction mechanisms are complex and diverse, and the relationships between the mechanisms are unclear, which limit the practical applications of the model. This article reviews the in vivo metabolism of D-galactose and the various mechanisms involved in the induction of brain aging, as well as the links between the mechanisms, to provide a reference for the application and development of this model and the in-depth study of brain aging.

    Reference
    Related
    Cited by
Get Citation

Copy
Share
Article Metrics
  • Abstract:
  • PDF:
  • HTML:
  • Cited by:
History
  • Received:March 05,2024
  • Online: November 19,2024
Article QR Code
You are the first Visitors
® 2025 All Rights Reserved
Address：5 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China Postcode： Phone：86-10-67779337 E-mail:bjb@cnilas.org
Supported by:Beijing E-Tiller Technology Development Co., Ltd.