Analysis of the construction and practice of an animal biosafety level-3 simulated laboratory
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Affiliation:

1. National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), Chinese Center for Disease Control and Prevention, Beijing 102206, China. 2. State Key Laboratory on Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054. 3. Sichuan Center for Diseases Control and Prevention, Chengdu 610044

Clc Number:

R-33

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    Abstract:

    An animal biosafety level-3 laboratory (ABSL-3) is a high-level biosafety installation that can conduct experiments on animals infected with highly pathogenic microorganisms. In recent years, with the continuous characterization of emerging and re-emerging infectious diseases, high-level biosafety laboratories have played increasingly important roles in pathogenic mechanism and drug and vaccine research and development. The demand for ABSL-3 is increasing year by year. At the same time, there is also a growing demand for personnel who are competent in working in ABSL-3. The systematization, normalization, and standardization of pre-service training have become important to guarantee a reduction in the risks to personnel working in ABSL-3. Training of ABSL-3 staff needs to be carried out in specific simulated laboratories. Therefore, it is necessary to construct simulated ABSL-3 and establish scientific and effective operating standards and mechanisms. This paper comprehensively introduces the design, construction, operation,and functions of a simulated ABSL-3 installation

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History
  • Received:February 27,2024
  • Online: July 16,2024
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