Advances in the study of glucose metabolic reprogramming in the pathogenesis of Alzheimer’s disease

doi:10.3969/j.issn.1671-7856.2024.04.019

Home > Archive>Volume 34, Issue 4, 2024 >156-164. DOI:10.3969/j.issn.1671-7856.2024.04.019

Advances in the study of glucose metabolic reprogramming in the pathogenesis of Alzheimer’s disease
DOI:
                        10.3969/j.issn.1671-7856.2024.04.019
                    
CSTR:
                        [cstr]
                    
Author:
                        XU Qian1XU Qian
1. Clinical College of Traditional Chinese Medicine, Hubei University of Traditional Chinese Medicine, Wuhan 430061, China
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
YANG Qiong1,2YANG Qiong
1. Clinical College of Traditional Chinese Medicine, Hubei University of Traditional Chinese Medicine, Wuhan 430061, China.2. Department of Geriatrics, Affiliated Hospital of Hubei University of Traditional Chinese Medicine / Hubei Hospital of Traditional Chinese Medicine / Hubei Academy of Traditional Chinese Medicine, Wuhan 430061
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site
TAN Zihu2TAN Zihu
2. Department of Geriatrics, Affiliated Hospital of Hubei University of Traditional Chinese Medicine / Hubei Hospital of Traditional Chinese Medicine / Hubei Academy of Traditional Chinese Medicine, Wuhan 430061
Find this author on All Journals
Find this author on BaiDu
Search for this author on this site

                    
Affiliation:1. Clinical College of Traditional Chinese Medicine, Hubei University of Traditional Chinese Medicine, Wuhan 430061, China.2. Department of Geriatrics, Affiliated Hospital of Hubei University of Traditional Chinese Medicine / Hubei Hospital of Traditional Chinese Medicine / Hubei Academy of Traditional Chinese Medicine, Wuhan 430061
Clc Number:R-33
Fund Project:

Article

Figures

Metrics

Reference

Cited by

Materials

Comments

Abstract:

Alzheimer’ s disease ( AD) is a neurodegenerative disorder characterized by widespread dementia.Despite the extensive research conducted on the pathogenesis of AD over the past 50 years, the underlying mechanisms responsible for AD-related cellular damage and cognitive impairment remain elusive. Multiple studies have confirmed alterations in the glucose metabolism patterns occur within the nerve cells of individuals with AD. This metabolic transition plays a crucial role in cell survival and disease progression, occurring decades before pathological changes and cognitive dysfunction even manifest. This article provides an overview of the potential mechanisms through which glucose metabolism reprogramming contributes to AD development in various types of nerve cells and brain regions, as well as the implication of their interplay. We aim to establish a foundation for further investigations into AD while offering insights and ideas for the development of novel preventive and therapeutic approaches.

Key words:Alzheimer’s disease; nerve cells; glucose metabolic reprogramming; research progress

Get Citation

Copy

Article Metrics

Abstract:193
PDF: 1347
HTML: 0
Cited by: 0

History

Received:November 30,2023
Revised:
Adopted:
Online: June 20,2024
Published:

Home

About this journal

Editorial Board

Info for Author

Contact Us

中文版

Get Citation

Share

Article Metrics

History

Article QR Code