慢性阻塞性肺疾病动物模型的造模方法
作者:
作者单位:

1.北京中医药大学,北京 100029; 2.中日友好医院肺病科 中日友好医院呼吸中心 国家呼吸疾病临床 研究中心,北京 100029

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R-33


Methods for animal models of chronic obstructive pulmonary disease
Author:
Affiliation:

1.Beijing University of Chinese Medicine,Beijing 100029,China. 2.Department of TCM Pulmonary Diseases, China-Japan Friendship Hospital. Center of Respiratory Medicine, China-Japan Friendship Hospital. National Clinical Research Center for Respiratory Diseases,Beijing 100029

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    摘要:

    慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD,以下简称为慢阻肺)是一种气道炎症性疾病,具有较高的发病率及病死率,给患者及社会带来沉重负担,目前对其发病机制及治疗方法仍未研究透彻。尽管动物模型仅能模拟疾病的部分特征,但它们对于进行慢阻肺生理病理、治疗的进一步研究是不可或缺的。本文结合 PubMed 收录的近三年慢阻肺造模相关文献,总结慢阻肺动物模型的模型动物种类、造模方法及测量指标

    Abstract:

    Chronic obstructive pulmonary disease(COPD) is a kind of airway inflammatory disease, which has a high morbidity and mortality, and brings heavy burden to patients and society. And its pathogenesis and treatment methods have not been thoroughly studied at present. Although animal models can only simulate part of the characteristics of the disease, they are indispensable for further research on the physiology, pathology and treatment of COPD. This paper summarizes the animal models, modeling methods and measurement indexes of animal models of COPD in combination with the literatures relevant to COPD modeling in recent three years in PubMed

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引用本文

刘 迪,张洪春.慢性阻塞性肺疾病动物模型的造模方法[J].中国比较医学杂志,2020,30(3):108~114.

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  • 收稿日期:2019-11-07
  • 在线发布日期: 2020-08-19
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