Polycystic ovary syndrome ( PCOS) is a gynecological metabolic and endocrine disorder of unknown etiology. Exploring different PCOS animal models might help reveal the etiology of PCOS and establish prevention and treatment measures. In this paper, we searched China National Knowledge Infrastructure (CNKI) for “ polycystic ovary syndrome + animal model” and PubMed for “ polycystic ovary syndrome + animal model ”, excluding reviews and theoretical literature. We found 231 articles from 1989 to 2018, and PCOS animals included research literature on rodent, non-human primate, and ruminant models. This study evaluated similarities between different animal models and human PCOS, to indicate the optimal model for different research purposes of PCOS disease research.