Allergic diseases have become a global public health problem that not only affects the quality of life of patients, but can also be life threatening. Using mouse models, a large number of molecular mechanisms and conformational changes of various allergic diseases have been revealed, such as allergic conjunctivitis, allergic asthma, contact dermatitis and food allergy. Although the types and phenotypes of immune responses in allergic mice with different diseases vary, they are similar to the immune responses and phenotypic changes that occur in humans. In this review, we summarize the common method for establishing mouse models of allergic diseases and describing the phenotypic changes of each. We hope that this review will provide a reference for the continued establishment and quality evaluation of allergic animal models in mice.