Objective A heat pipe air heat exchanger is used to exchange the heat of gas discharged from experimental animal facilities, the energy of which is recovered. To save energy and reduce emissions, the recycled energy is utilized in the fresh air to reduce energy consumption. Methods A heat pipe air heat exchanger was used for exchanging heat between the intake and exhaust systems of an experimental animal facility. Results The experimental animal facility recovered the energy in the exhaust air by using a heat pipe air heat exchanger to exchange heat. This can save about 45% of energy throughout the year. Conclusions The heat pipe air heat exchanger is suitable for situations in which indoor and outdoor temperatures differ significantly. The system requires a large amount of air exchange and it can produce guaranteed heat in air-conditioning facilities. The energy-saving effect of the heat pipe air heat exchanger is remarkable, and it can achieve energy-saving and emissions reduction, which has huge social and economic benefits.