浙江省科技计划项目（2013C37010）。
目的 分析包括白毛黑眼兔在内的四个品种实验兔的虹膜和皮肤组织中的黑色素分布情况和相互之间的差异。 方法 通过组织切片和硫酸亚铁染色，对四个品种实验兔的虹膜和皮肤组织中的黑色素含量和分布进行了观察与比较。结果 与其背景白化品种相比，白毛黑眼兔不仅在虹膜组织中出现了类型完整的黑色素，而且在其表型为白色的皮肤的毛囊中也出现了低含量的黑色素。结论 本结果为白毛黑眼兔突变表型机理研究提供了一定线索。
Objective To identify and compare melanin distribution in iris and skin tissues of rabbits from four breeds including WHBE rabbit. Methods Ferrous sulphate staining was performed for iris and skin tissue of rabbits from different breeds. Results It showed dark green staining in both iris stroma and iris pigment epithelium of WHBE rabbit, while light green staining was observed in its follicles. Conclusion The results of histologic evaluations provide some clues to the future research on mechanism of WHBE rabbit phenotype mutation.
朱亮,屠珏,黄宇,陈诚.白毛黑眼兔等四种实验兔黑色素分布的组织学观察与比较[J].中国比较医学杂志,2014,24(9):59~61.
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