大型实验动物屏障设施环境微生物和尘埃粒子的动态监控
作者:
作者简介:

王晶(1984-),男,硕士, E-mail:himrwang@163.com。

基金项目:

国家科技支撑项目2006BAI23B04,上海市科研计划项目08140900800。


Dynamic Monitoring of Bacteria and Dust Particles in Barrier Animal Facilities
Author:
  • 摘要
  • | |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • | |
  • 文章评论
    摘要:

    目的本实验以大型实验动物屏障设施为研究对象,分析屏障设施的环境微生物及尘埃粒子的动态变化规律及其相关影响因素。 方法测定屏障设施各功能区域不同时间及不同工作状态下空气落下菌和直径≥0.3 μm尘埃粒子的数量变化。结果屏障系统落下菌与尘埃粒子变化规律如下:屏障系统内空气落下菌与尘埃粒子在饲养工作后显著升高,喷雾消毒后明显降低;大、小鼠饲育室空气落下菌与尘埃数在凌晨时明显升高,而兔饲育室在凌晨时间段则较低;清洁走廊和污染走廊在工作状态时细菌含量明显上升,非工作状态时细菌含量一直处于较低的水平。结论实验动物屏障系统的环境微生物与尘埃粒子的动态数量变化与动物品种、空气消毒、人员进出及动物室内的饲养操作等有关。

    Abstract:

    ObjectiveTo study the dynamic changes of becteria and the dust particles in barrier animal facilities. MethodsTo measure the quantity of falling bacteria and dust particles of larger than or equal 0.3 μm in diameter at different times and in the different functional areas of the barrier animal facilities. ResultsThe quantity of falling bacteria and dust particles were significantly increased in barrier animal room after breeding operation, and was the lowest after spray disinfection. There was a high quantity of bacteria and dust at 00∶00 in the mice and rats breeding room, but was a valley value in the rabbits breeding room at the same time. The quantity of falling bacteria and dust particles was significantly increased in the clean and semi-clean corridor at working time, and was kept a relatively stable level at non-working times. ConclusionsThere are regular changes of the quantity of falling bacteria and dust particles in barrier animal facilities, and these changes are related with animal species, spray disinfection, mobility of persons and materials and operation of animal care.

    参考文献
    相似文献
    引证文献
引用本文

王晶,刘伟,袁水娟,谈小倩,谢恩,徐平,芮荣.大型实验动物屏障设施环境微生物和尘埃粒子的动态监控[J].中国比较医学杂志,2012,(2):61~65.

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
防诈骗提示!请勿点击不明链接或添加个人微信。编辑部所有邮箱后缀均为@cnilas.org
关闭