The anatomical and the histological properties of albino Chinese hamsters were observed and compared with those of Chinese hamsters and laboratory rats and mice. The results showed that 1. The testes of the albino Chinese hamsters developed normally and were much bigger than those of the same-sized laboratory mice, so the animal might be used as a model for the test of drug reproduction toxicity and the reproduc-tive studies.2.The wall of the cheek pouch was thin and the capillaries could be seen clearly, perhaps being a good material in making researches on microcircu-lation and tumor transplantation. 3. The bronchiolar epithelium, which is different from that of rats and mice, was pseudostratified columnar in nature, and was very like that of the human race.4.The spleen was smaller as compared with that of Chinese hamsters and the white pulp was underdevelop-ed, suggesting that the immunological function might be slightly lower.5.The eyeball was approximately 3 times heavy as that of mice. and 6. The animal had not any gall bladder.