| 楼金成,苗镡允,苏嘉琪,胡 情,翟春涛,吕玉娥.过敏性哮喘大鼠模型的建立方法与评价[J].中国比较医学杂志,2023,33(1):130~137. |
| 过敏性哮喘大鼠模型的建立方法与评价 |
| Establishment and evaluation of rat model of allergic asthma |
| 投稿时间：2022-05-19 |
| DOI：10. 3969 / j.issn.1671-7856. 2023. 01. 017 |
| 中文关键词: 过敏性哮喘 大鼠模型 模型建立 评价指标 |
| 英文关键词:allergic asthma rat model model establishment evaluation index |
| 基金项目: |
|
| Author Name | Affiliation | | LOU Jincheng | Shanxi University of Traditional Chinese Medicine, Jinzhong 030600, China | | MIAO Xinyun | Shanxi University of Traditional Chinese Medicine, Jinzhong 030600, China | | SU Jiaqi | Shanxi University of Traditional Chinese Medicine, Jinzhong 030600, China | | HU Qing | Shanxi University of Traditional Chinese Medicine, Jinzhong 030600, China | | ZHAI Chuntao | Shanxi University of Traditional Chinese Medicine, Jinzhong 030600, China | | LYU Yue | Shanxi Province Acupuncture Hospital, Taiyuan 030006 |
|
| 摘要点击次数: 522 |
| 全文下载次数: 175 |
| 中文摘要: |
| 过敏性哮喘是一种 2 型炎症反应介导的超敏反应所引起的气道慢性损伤性炎症疾病。目前尚无任何一种哮喘动物模型能完全概括人类过敏性哮喘的发生发展过程,因此构建一个较为完善且稳定的、符合临床患者病理表现的过敏性哮喘动物模型尤为重要。本文就近5年过敏性哮喘模型大鼠的品系选择、造模方法、模型评价指标等方面做简要的分析。 |
| 英文摘要: |
| Allergic asthma is a chronic airway inflammatory disease caused by type 2 inflammatory response- mediated hypersensitivity. At present, no animal model of asthma that completely recapitulates the occurrence and development of allergic asthma in humans is available. Therefore, it is particularly important to establish a relatively complete and stable animal model of allergic asthma that conforms to the pathological manifestations of patients. This review briefly analyzes the strain selection, modeling method, and model evaluation indicators of allergic asthma model rats in the past 5 years. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
