| 赵勇,伍静,毛峰峰,赵善明,张彩琴,白冰,师长宏.裸鼠荷瘤实验中常见问题的解析和总结[J].中国比较医学杂志,2012,(7):17~20. |
| 裸鼠荷瘤实验中常见问题的解析和总结 |
| Summarize of the Common Problem and the Experience of Tumor-burdened in Nude-mice |
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| DOI：10.3969.j.issn.1671.7856.2012.007.005 |
| 中文关键词: 裸鼠 肿瘤 模型, 动物 |
| 英文关键词:Nude mice Tumor Model,animal |
| 基金项目: |
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| Author Name | Affiliation | | ZHAO Yong | Laboratory Animal Center of Fourth Military Medical University, Xi''an 710032, China | | WU Jing | Laboratory Animal Center of Fourth Military Medical University, Xi''an 710032, China | | MAO Feng-feng | Laboratory Animal Center of Fourth Military Medical University, Xi''an 710032, China | | ZHAO Shan-min | Laboratory Animal Center of Fourth Military Medical University, Xi''an 710032, China | | ZHANG Cai-qin | Laboratory Animal Center of Fourth Military Medical University, Xi''an 710032, China | | BAI Bing | Laboratory Animal Center of Fourth Military Medical University, Xi''an 710032, China | | SHI Chang-hong | Laboratory Animal Center of Fourth Military Medical University, Xi''an 710032, China |
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| 中文摘要: |
| 目的探讨裸鼠荷瘤过程中的出现的常见问题,提高裸鼠荷瘤的成功率。方法通过分析实验过程中影响裸鼠荷瘤的各种因素,寻求裸鼠荷瘤常见问题的解决方案。结果总结了在裸鼠荷瘤实验中的各种影响因素,并提出了合理的建议。结论裸鼠肿瘤模型的制备是研究肿瘤学、免疫学、药品与生物制品的安全性评价以及有效性筛选等研究课题的基础,本文为制备良好的裸小鼠肿瘤模型提供合理的建议。 |
| 英文摘要: |
| ObjectiveDiscussion the common problem of tumor-burdened in node-mice,In order to improve the success rate of tumor burden. MethodThrough analysis the influence of various factors of tumor-burden in node-mice, seek the solution of problem in tumor burdended. ResultSummarized the various factors in the tumor burden, and put forward reasonable suggestions.ConclusionNode-mice tumor burden is the base of the oncology, drug and biological products of safety evaluation and effectiveness screening. This paper is to provide reasonable suggestions for the preparation of good nude mice tumor model. |
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