With the outbreak of the novel coronavirus pneumonia, coronavirus disease 2019 ( COVID-19), research on the pathogenesis and functional structure of the causative virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as on COVID-19-related vaccines and drugs, has accelerated rapidly. Animal infection models, especially those using non-human primates, are indispensable for research on COVID-19. Owing to their physiological similarity to humans, non-human primate models are among the most important animal models in SARS-CoV-2 research. However, there are relatively few studies using non-human primate infection models for COVID-19 owing to various constraints, including ethics, research qualifications, and cost; therefore, it is particularly critical to ensure the validity of each animal test result . This article summarizes and analyzes evaluation indicators for the non-human primate model of SARS-CoV-2 infection, including clinical scores, imaging diagnosis, hematology indicators, and pathogens, from the published literature on SARS-CoV-2-infected animal models and clinical data, which could provide a useful reference for the successful establishment of more effective non-human primate models of SARS-CoV-2 infection.